The biotech Regeneron Pharmaceuticals has now produced strong hints that monoclonal antibodies, synthetically produced versions of proteins made by the immune system, can work as treatments in people who are infected with the pandemic coronavirus but are not yet seriously ill.
A new scientific report confirms that cats and dogs can be infected by the novel coronavirus, and that neither animal is likely to get sick. Cats, however, do develop a strong, protective immune response, which may make them worth studying when it comes to human vaccines.
Yale researchers found that the coronavirus can directly infect brain cells, potentially eliciting neurological symptoms — such as the loss of taste or smell — observed in 40 to 60 percent of COVID-19 patients.
ASt. Louis startup has licensed a COVID-19 vaccine developed at Washington University that won’t be one of the first on the market, but could have advantages over other early vaccine contenders.
Studies could advance treatments for all patients infected with SARS-CoV-2.
A team of researchers set out to determine if circulating baseline T cell signatures are linked to a lack of viral control and severity of disease upon SARS-CoV infection.
Scientists at the University of Pittsburgh School of Medicine say they have discovered a super-potent molecule that was "highly effective" at preventing and treating COVID-19 when tested in mice and hamsters.
The coronavirus that causes COVID-19 can sometimes hijack brain cells, using the cells' internal machinery to copy itself, according to a new study.
A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation.
Researchers at the University of Pittsburgh have isolated a biomolecule that they say neutralizes the virus that causes COVID-19 "completely and specifically."
Giving patients antibodies against the virus that causes COVID-19 could provide a new treatment for the disease, particularly for those who are not sick enough to be in the hospital, an Augusta University expert said.
As leading pharmaceutical and biotechnology companies fast-track COVID-19 vaccines through clinical trials, smaller developers face a battle to get their candidates noticed.
Pfizer and its partner BioNTech have five potential COVID-19 vaccines in clinical trials, each of which is based on a different mRNA format. Now the companies are reporting that the most advanced candidate, BNT162b2, performed well in trials in which mice and macaques were infected with the coronavirus after inoculation.
Based on three preclinical mouse studies, VBI Vaccines has selected two potentially one-dose vaccine candidates for its VBI-2900 coronavirus program.
People severely ill with COVID-19 are less likely to die if they are given drugs called corticosteroids than people who are not, according to an analysis of hospital patients on five continents.
The findings raise the distant possibility that they could become a reservoir for the pathogen in nature and transmit it to humans.
Researchers have developed a novel vaccine using nucleotide untranslated regions that successfully protected mice from COVID-19.
A blood test on hospital admission showing the presence or absence of SARS-CoV-2 can identify patients at a high risk of severe COVID-19, according to researchers. Admitted patients without virus in their blood have a good chance of rapid recovery.
AstraZeneca trial will recruit up to 30,000 participants, with a goal to develop and confirm an effective vaccine to prevent COVID-19 by end of year.
In animal studies, nanoparticle treatment induces antibodies against SARS-CoV-2.
Top University of South Carolina researchers think the chemical in marijuana that induces a “high” may be effective in treating a potentially lethal coronavirus complication, according to three newly released studies.
'Disease tolerance' is the ability of an individual, due to a genetic predisposition or some aspect of behavior or lifestyle, to thrive despite being infected with an amount of pathogen that sickens others. It might play a role in asymptomatic coronavirus infections.
Here, we describe parallel efforts using both humanized mice and convalescent patients to generate antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, which yielded a large collection of fully human antibodies that were characterized for binding, neutralization, and three-dimensional structure.
Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose and is effective in preventing infection in mice susceptible to the novel coronavirus.
A saliva-based COVID-19 laboratory diagnostic test developed by researchers at the Yale School of Public Health has been granted an emergency use authorization by the U.S. Food and Drug Administration (FDA).
